|
KMID : 0366220090440020100
|
|
Korean Journal of Hematology
2009 Volume.44 No. 2 p.100 ~ p.103
|
|
|
Mutation of the N-ras Gene in a Patient Suffering from the Blast Phase of Chronic Myelogenous Leukemia
|
|
Song Sung-Heon
Choi Jung-Hye
Kim In-Soon
Kim Byoung-Kook
Lee Young-Yiul
Park Byeong-Bae
Roh Young-Wook
Ahn Yong-Woo
Kim Yeon-Jae
Byoun Young-Sang
Choi Ji-Young
Hwang Deok-Won
|
|
|
Abstract
|
|
|
|
The blast phase in chronic myelogenous leukemia (CML) is associated with mutation of several genes. It is well known that p53 gene mutation plays a key role in the myeloid or lymphoid blast phase of CML. But for the case of the N-ras gene, the association between N-ras mutations and the blast phase of CML is not yet known. We report here on a case of detecting N-ras point mutation without p53 mutation in a 64 year-old man who suffered from the lymphoblastic blast phase of CML. (Korean J Hematol 2009;44:100-103.)
|
|
|
KEYWORD
|
|
|
Chronic myelogenous leukemia, Gene mutation, Blast phase, N-ras
|
|
|
FullTexts / Linksout information
|
|
  
|
|
|
Listed journal information
|
|
  
|